Metabolism Alprazolam is extensively metabolized in human beings, generally by cytochrome P450 3A4 (CYP3A4), to 2 key Lively metabolites within the plasma: 4-hydroxyalprazolam and ?-hydroxyalprazolam. The plasma circulation levels of The 2 Lively metabolites are under four% on the mum or dad. The described relative potencies in benzodiazepine recep